Molecular regulatory mechanism of tooth root development
نویسندگان
چکیده
منابع مشابه
Cellular and molecular mechanisms of tooth root development.
The tooth root is an integral, functionally important part of our dentition. The formation of a functional root depends on epithelial-mesenchymal interactions and integration of the root with the jaw bone, blood supply and nerve innervations. The root development process therefore offers an attractive model for investigating organogenesis. Understanding how roots develop and how they can be bio...
متن کاملMolecular genetics of tooth development.
Organogenesis depends upon a well-ordered series of inductive events involving coordination of molecular pathways that regulate the generation and patterning of specific cell types. Key questions in organogenesis involve the identification of the molecular mechanisms by which proteins interact to organize distinct pattern formation and cell fate determination. Tooth development is an excellent ...
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Tooth root formation begins after the completion of crown morphogenesis. At the end edge of the tooth crown, inner and outer enamel epithelia form Hertwig's epithelial root sheath (HERS). HERS extends along with dental follicular tissue for root formation. Ameloblastin (AMBN) is an enamel matrix protein secreted by ameloblasts and HERS derived cells. A number of enamel proteins are eliminated i...
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ژورنال
عنوان ژورنال: International Journal of Oral Science
سال: 2012
ISSN: 1674-2818,2049-3169
DOI: 10.1038/ijos.2012.61